Save
Autologous adipose-derived stem cells in early knee osteoarthritis: identification of a subpopulation with greater response
ESSKA Academy. Schiavone Panni A. Nov 8, 2019; 284359; epEKA-12
Prof. Alfredo Schiavone Panni
Prof. Alfredo Schiavone Panni
Login now to access Regular content available to all registered users.

You can access free non-premium educational content on the ESSKA Academy Portal by registering for free as 'ESSKA Academy User' here
Abstract
Discussion Forum (0)
Rate & Comment (0)
Autologous adipose-derived stem cells in early knee osteoarthritis: identification of a subpopulation with greater response

ePoster - epEKA-12

Topic: TKA

Vasso M., Braile A., Toro G., De Cicco A., Lepore F., Schiavone Panni A.
University of Naples, Multidisciplinary Department of Medico-Surgical and Dentistry Specialties, Naples, Italy

Purpose: The purpose of this study was to report the clinical and functional results of a series of patients with early knee osteoarthritis (KOA) treated with the intra-articular injection of autologous adipose-derived stem cells (aASCs) plus arthroscopic debridement. The hypothesis was that protocol would significantly improve the clinical and functional outcomes in patients with early KOA.
Methods: 52 patients with early KOA who received arthroscopic debridement followed by percutaneous injection of aASCs, were enrolled into the study and retrospectively analyzed with an average follow-up of 15.3 (range, 6 to 24) months. Patients were assessed through the IKS knee and function scores and VAS pain scale.
Results: The mean IKS knee score improved from 37.4 (range, 14 to 79) points preoperatively to 62.6 (range, 27 to 95) points at the latest follow-up (p < < 0.01). The mean IKS function score improved from 57.2 (range, 25 to 100) points preoperatively to 83.0 (range, 35 to 100) points at the latest follow-up (p < < 0.01). The mean VAS score decreased from 8.5 (range, 3 to 10) preoperatively to 5.1 (range, 0 to 8) at the latest follow-up (p < < 0.01). Additionally, patients with a preoperative VAS score greater than eight were found to show greater clinical and functional benefits compared with patients with VAS score lower than eight.
Conclusions: The knee injection of aASCs associated to arthroscopic debridement increased significantly the clinical and functional scores in patients with early KOA at a mid-term follow-up, especially those with higher preoperative VAS scores.
Code of conduct/disclaimer available in General Terms & Conditions
Anonymous User Privacy Preferences

Strictly Necessary Cookies (Always Active)

MULTILEARNING platforms and tools hereinafter referred as “MLG SOFTWARE” are provided to you as pure educational platforms/services requiring cookies to operate. In the case of the MLG SOFTWARE, cookies are essential for the Platform to function properly for the provision of education. If these cookies are disabled, a large subset of the functionality provided by the Platform will either be unavailable or cease to work as expected. The MLG SOFTWARE do not capture non-essential activities such as menu items and listings you click on or pages viewed.


Performance Cookies

Performance cookies are used to analyse how visitors use a website in order to provide a better user experience.



Google Analytics is used for user behavior tracking/reporting. Google Analytics works in parallel and independently from MLG’s features. Google Analytics relies on cookies and these cookies can be used by Google to track users across different platforms/services.


Save Settings